OH!

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Compounded · Prescription · Reviewed by a licensed clinician

Arousal difficulty is physical. And it might be treatable.

Reduced arousal and lubrication are among the most commonly reported women's health concerns, and among the least often treated. OH! connects you with a licensed clinician who reviews your health history and, if appropriate, prescribes a topical treatment. Delivered in unmarked packaging.

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Clinician-reviewed Prescription only Unmarked packaging Cancel anytime Clinician-reviewed Prescription only Unmarked packaging Cancel anytime
The clinical picture

It's a blood flow problem, not a willpower problem.

Physical arousal depends on genital blood flow, nerve response, and tissue sensitivity. All three are affected by hormonal change, common medications, circulation, and sleep. When they decline, the physical response declines with them, regardless of how you feel about your partner or yourself.

~50%

of women in midlife report poor sexual wellbeing.

Monash University midlife study ↗
2×

the likelihood of desire and arousal difficulty in early perimenopause versus premenopause.

Monash University midlife study ↗
25–30%

report reduced lubrication, among the most common menopause-related symptoms.

Menopause symptom prevalence (NIH PMC) ↗
·Perimenopause and menopauseDeclining estrogen reduces genital blood flow and tissue elasticity.
·SSRIs and SNRIsAntidepressant-associated sexual dysfunction is common and frequently undiscussed.
·Hormonal contraceptionCan affect free testosterone and lubrication in some women.
·Cardiovascular and metabolic healthArousal is vascular. Circulation matters here as it does elsewhere.
·Postpartum recoveryHormonal shifts and tissue healing can persist well past six weeks.
·Sleep debt and chronic stressElevated cortisol suppresses the physical arousal response.

About these figures. Each number describes how common these experiences are among women generally, drawn from peer-reviewed research and established medical references and linked to its source above. None describes what any treatment does, and none is a claim about outcomes from OH! Prevalence estimates vary between studies depending on population and definition. Further reading: StatPearls, Female Sexual Interest & Arousal Disorder · Boston University, Epidemiology of FSD.

Roughly half of women in midlife report a problem.
Most never bring it up. Most doctors never ask.

OH! · Est. 2026

Monash University midlife study  ·  Sarin et al., PLOS ONE  ·  Boston University School of Public Health

Why you may not have heard of this

The option existed.
Almost nobody was told.

Compounding pharmacies have prepared topical treatments for arousal difficulty for years, and clinicians have prescribed them off-label. There is peer-reviewed literature on them. What there has never been is a company willing to talk about it plainly.

Why haven't you heard about it?

Because it travelled by word of mouth. If your gynecologist happened to know, you could get it. If not, you were told to have a glass of wine and relax. Formulations vary widely between pharmacies, and essentially no one has marketed the category or explained it.

What we're doing differently

We're not inventing it. We're talking about it and treating it like the medical option it always was: we are designing our formula with ingredients we wish were in every formulation. We are offering two strengths of sildenafil, the active ingredient in Viagra, because we know some women will need a little extra oomph. We're working with specialized compounding pharmacies and clinicians who care. No wink, wink, nudge, nudge.

Compounded topical preparations for female sexual arousal disorder are prepared by licensed compounding pharmacies under Section 503A and prescribed off-label. They are not FDA approved, formulations differ between pharmacies, and the evidence base varies by ingredient. See the scoping review in The Journal of Sexual Medicine.

What's in it

Seven ingredients.
Each one has a job.

Two strengths. One formula. Applied where it counts.

Sildenafil

(The active ingredient in Viagra®)

Nifedipine

(Keeps blood vessels open)

L-arginine

(Fuels nitric oxide for blood flow)

Glycerin

(Moisture for glide)

Oxytocin

(Supports serotonin for libido)

Zinc

(Supports sensitive skin)

Peppermint

(A cool tingle on contact)

What's not in it: testosterone, aminophylline, or anything that needs extra bloodwork.

Original contains 3% sildenafil. Extra Strength contains 5%. Viagra is a registered trademark of Viatris Inc. OH! is not affiliated with or endorsed by Viatris. Compounded medications are not FDA approved, and the FDA has not evaluated this formulation for safety, effectiveness, or quality. Individual results vary.

Choose your plan

Pick your strength.

A prescription compounded arousal cream, delivered every 1, 2 or 3 months.

  • ·Applied 15 to 30 minutes before, not taken daily
  • ·Single-use 3 mL packets. No jar, no measuring
  • ·Reviewed and prescribed by a licensed clinician
  • ·Unmarked box. Cancel anytime
Choose strength

Where most women start.

Choose frequency

15 packets per box.

$175/ box
$11.67 a packet · Billed monthly

Plus a yearly clinician visit: $25 online, or $35 if your state requires video.

Try OH!

Prescription required. A licensed clinician reviews your intake and confirms the strength that's right for you. Recurring charge each time a box ships, cancel anytime. Compounded medications are not FDA approved.

Important to know

What is OH!?

A prescription topical cream for women, applied externally 15 to 30 minutes before sex. It combines sildenafil, the same active ingredient as Viagra, with supporting ingredients that work on local blood flow and sensation.

It's compounded: a state-licensed pharmacy prepares it against a prescription written for you. Compounded medications are not FDA approved, and the FDA has not evaluated this formulation for safety, effectiveness, or quality.

Original vs. Extra Strength

Same formula. Different sildenafil concentration. Original is 3%. Extra Strength is 5%. Everything else in the packet is identical.

How many doses do I get?

Every monthly fill is 15 single-use packets. One packet is one use, and nothing ships without a prescription.

Safety information

Do not use OH! if you take nitrates (such as nitroglycerin, for chest pain) or riociguat. Combining them with sildenafil can cause a dangerous drop in blood pressure.

Tell your clinician about every medication you take, especially blood pressure medications, alpha blockers, and other PDE5 inhibitors, and if you are pregnant, breastfeeding, or have a history of heart disease, low blood pressure, or stroke. Your intake covers all of this.

For external use only. Stop using it and contact your clinician if you have irritation, burning that doesn't fade, dizziness, or any reaction that worries you. In an emergency, call 911.

How it works

Three steps. No waiting room.

01

Health review

A private online questionnaire covering your symptoms, health history, and current medications. A few minutes, and often no video call at all, though some states require a short live consult before a first prescription. We'll schedule a call if your state requires it.

02

Clinician assessment

A licensed clinician reviews your intake and determines whether treatment is appropriate, or tells you honestly if it isn't, and what else to consider.

03

Delivery

An unmarked box with no branding and no product name on the label. Refills monthly, with ongoing clinician messaging included.

Privacy

A medical decision about your own body.

Health information is sensitive, and this category more than most. Every touchpoint is built for privacy.

OH! OH!
Try OH!

Find out if this is right for you.

Be first in line for clinician review when we launch this fall.

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Questions

Common questions

Is something wrong with me?
No. Reduced arousal is one of the most commonly reported women's health concerns, and prevalence rises substantially in midlife: roughly half of women in midlife report poor sexual wellbeing, and early perimenopause roughly doubles the likelihood of arousal difficulty. Common contributors include hormonal change, SSRIs and other medications, circulation, sleep, and chronic stress. It's physiology, and it might be treatable.
Is this hormone therapy?
No. OH! is prescribed and reviewed separately from hormone therapy, and it works locally on blood flow rather than systemically. The exact ingredients depend on the formula a clinician prescribes for you, which they'll walk through with you before you fill anything, including whether it affects your hormone levels or cycle.
Does this affect my partner?
For most people this doesn't require a conversation, the same way a man taking Viagra doesn't announce it. To keep the cream on you, use a condom or dental dam, or do a quick wipe before oral or other contact if you have concerns. That covers most of the concern, though not all of it. The one exception worth knowing regardless: if a partner takes nitrate medication for chest pain or heart problems, mention it, since that interaction carries real risk. Ask your clinician what's right for your situation.
How is this different from a lubricant?
Lubricants reduce friction. OH! is a prescription medication that acts on blood flow to the tissue itself, a different mechanism addressing a different part of the problem. That's also why it requires clinician review: it's a drug, not a cosmetic product.
Why does it require a prescription?
Because OH! is a prescription medication with real contraindications, including interaction with nitrate medications and caution with certain cardiovascular conditions. A licensed clinician has to review your health history and current medication list before determining whether it's appropriate for you.
What does “compounded” mean, and should that worry me?
It means a state-licensed pharmacy prepares your medication to order against a prescription written for you, instead of dispensing something mass-produced. This is ordinary pharmacy practice, and it is how most conditions without an approved drug get treated. There is no FDA-approved treatment indicated for female sexual arousal disorder, so compounding is the only route that exists today. What you should know honestly: compounded medications are not FDA approved, and the FDA does not evaluate them for safety, effectiveness, or quality, even when the pharmacy is licensed and inspected by its state board. The upside is real too: a clinician can adjust the strength for you, which a boxed product cannot do. We will name our pharmacy publicly before we take an order, so you can look them up yourself.
What are the possible side effects?
Reported effects with topical use are typically local and mild: warmth, flushing, or temporary sensitivity at the application site. Systemic effects can occur but are less common with topical delivery than with oral administration. A clinician will review the complete risk profile with you. This page is information, not medical advice, and it isn't a substitute for that conversation.
Will this address low desire as well?
Not directly, and we won't claim otherwise. OH! addresses the physical arousal response: blood flow and tissue sensitivity. Desire involves hormones, relationship context, stress, and mental load, which are separate systems. For some women the physical response is the missing piece; for others it's one part of a broader picture. That's why membership includes ongoing clinician messaging rather than just a monthly shipment.
What if I'm not eligible?
You aren't charged for medication. The clinician visit fee ($25 online, or $35 where your state requires video) still applies, since your clinician did the review. If they determine treatment isn't appropriate for you, we'll say so, explain why, and where we can, point you toward what might be worth discussing with your own doctor instead.
Can I cancel?
Any time, in one click, with no phone call and no retention offer. Skip your next box or leave entirely.